Process for producing A83850 antibiotics

Details Process for producing A83850 antibiotics Process for producing A83850 antibiotics

1990-08-16

1993-02-16

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

4352521, 435170, 530317, C12P 2104, C12P 104, C12N 120, C07K 512

Patent

active

051870827

ABSTRACT:
New glycopeptide antibiotic A83850, comprising A83850A, and A83850B, is produced by Amycolatopsis albus strain NRRL 18532. A83850A and A83850B can be reduced to give new biologically active derivatives. The A83850 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.

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patent: 4548925 (1985-10-01), Higgins et al.
patent: 4552701 (1985-11-01), Nagarajan et al.
patent: 4558008 (1985-12-01), Boeck et al.
Harris, C. M. et al., J. Am. Chem. Soc., 105 No. 23:6915-6922 (1983).
Lechevalier, M. P. et al., Int. J. Syst. Bacteriol., 36, No. 1:29-37 (1986).
Hessen, A. et al., Int. J. Syst. Bacteriol., 37, No. 3:292-295 (1987).

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