Process for producing a ribofuranose

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C548S262200

Reexamination Certificate

active

07034161

ABSTRACT:
A method of converting pure α-anomer or β/α-anomer mixtures of 1,2,3,5-tetra-O-acetyl-L-ribofuranose to methyl-1-(2,3,5-tri-O-acetyl-β-L-ribofuranosyl)-1,2,4-triazole-3-carboxylate an intermediate for levovirin, as well as, the novel pure α-anomer, alpha 1,2,3,5-tetra-O-acetyl-L-ribofuiranose, are useful in manufacturing levovirin.

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Basic Nucleic Acid Chemistry: vol. 1, Paul T'so, (ED) 1975, pp. 116-125.
Guthrie et al., Chem. Ind., pp. 547-548 (1968.
Ramasamy et al., J. Med. Chem., 43, pp. 1019-1028 (2000).

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