Process for producing a pharmaceutical tablet using a homozygous

Details Process for producing a pharmaceutical tablet using a homozygous Process for producing a pharmaceutical tablet using a homozygous

1992-04-10

1994-03-08

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

514778, 514960, 514961, A61K 948, A61K 4700

Patent

active

052925196

ABSTRACT:
The use of a starch obtained from a plant source that is homozygous in a white recessive gene, such as white common corn starch, has superior compression and ejection forces compared to commercial disintegrantants/binders. The starch derived from common corn containing the homozygous white recessive gene was also found to have comparable whiteness to commercial bleached corn starches used in tableting.

REFERENCES:
patent: 5139809 (1992-08-01), Wienan et al.
Gergelz et al; CA 115(12), 120090u (1991).
Bos et al, Pharm. Week 61. Sci. Ed. 9:274-282 (1987).
Nasipuri, et al, Smilers Chemist, "Pharm. Ind." 44:1288-1292 (12)(1982).

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