Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1983-11-15
1986-01-21
Marantz, Sidney
Drug, bio-affecting and body treating compositions
Lymphokine
424101, 435236, 435239, A61K 3912, A61K 3514, C12N 704, C12N 702
Patent
active
045656975
ABSTRACT:
A process for producing a hepatitis B infection preventing vaccine containing hepatitis B surface antigen as a main component thereof which comprises removing human plasma components possibly causing adverse effects and components capable of causing hepatitis B infection by incorporating steps of fractionation using ammonium sulfate, adsorption on a colloidal silicate and fractionation using polyethylene glycol into the purification stage after heat treatment and further carrying out a treatment for infectivity inactivation without causing any antigenicity impairment.
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Fujiwara Terufumi
Funakoshi Satoshi
Ohmizu Akimasa
Ohmura Takao
Foley Shawn P.
Green Cross Corporation
Marantz Sidney
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