Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...
Reexamination Certificate
2006-10-03
2006-10-03
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Solid support and method of culturing cells on said solid...
C427S553000, C427S532000, C427S554000, C427S558000, C435S029000, C435S395000
Reexamination Certificate
active
07115419
ABSTRACT:
A process for producing a film for controlling the chemotactic function in an extremely small area in which a chemotactic factor substance in the area has a concentration gradient in one direction. The invention further includes an artificial material with an arrangement in which, on a substrate, there is a film having a chemotactic factor substance for controlling the chemotactic function which it has a concentration gradient in one direction. The process of the invention includes controlling the amount of irradiation in one direction of the film such that the chemotactic factor substance is degenerated which results in a corresponding concentration gradient of the film in the one direction.
REFERENCES:
patent: 5821013 (1998-10-01), Miller et al.
patent: 6143477 (2000-11-01), Rhieu
patent: 282201 (1988-09-01), None
patent: 5-198499 (1993-08-01), None
Hypolite, CL et al. Formation of microscale gradients of protein using heterobifunctional photolinkers. Bioconjugate Chem. 1997. 8: 658-663.
Herbert, C. et al.: “Micropatterning gradients and controlling surface densities of photoactivatable biomolecules on self-assembled monolayers of oligo(ethylene glycol) alkanethiolates”, Chemistry & Biology, vol. 4, No. 10, Oct. 1997, pp. 731-737, XP002289422 *p. 731-733 *.
Ye Tao et al., “Photoreactivity of alkylsiloxane self-assembled monolayers on silicon oxide surfaces”, Langmuir, vol. 17, No. 15, Jul. 24, 2001, pp. 4497-4500, XP002289423 * p. 4497-p. 4498 *.
Lee, J. et al. “Interaction of cells on chargeable functional group gradient surfaces”, Biomaterials, Elsevier Science Publishers BV., Barking, GB, vol. 18, No. 4, Feb. 1, 1997, pp. 351-358, XP004017229, ISSN: 0142-9612, *the whole document*.
Control of Cell Function by Concentration-Gradient Pattern-Immobilized Biological Macromolecules, Mitsuko Hayashi et al., Polymer Preprints, Japan, Macromolecule Society Association, Sep. 20, 1999, vol. 48, No. 10, pp. 2411-2412.
Fernandez Susan E.
Lankford , Jr. Leon B.
Safran David S.
Ushiodenki Kabushiki Kaisha
LandOfFree
Process for producing a film for controlling the chemotactic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for producing a film for controlling the chemotactic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing a film for controlling the chemotactic... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3627800