Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-04-30
1999-01-19
Robinson, Douglas W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 276, 536 278, 536 2781, 544264, C07H 1916, C07D47300
Patent
active
058615032
ABSTRACT:
An efficient, regiocontrolled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F.sub.2 in He or other inert gas.
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Barrio Jorge R.
Namavari Mohammad
Phelps Michael E.
Satyamurthy Nagichettiar
Crane L. Eric
Robinson Douglas W.
The Regents of the University of California
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