Process for producing 3-deoxyguanosine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 87, 435 88, 435194, 435859, 435883, 435884, 435910, C12R 1265, C12R 1445, C12R 145, C12R 164, C12P 1930, C12P 1938, C12P 1940, C12N 912

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045943206

ABSTRACT:
Glycosylation or transglycosylation of a specified guanine derivative, namely 9-substituted or non-substituted guanine of formula [I] with a 3-deoxyribose donor such as 3'-deoxyadenosine in the presence of a nucleoside phosphorylase source such as of microorganism origin is disclosed. The nucleoside phosphorylase source is specified.

REFERENCES:
patent: 3269917 (1966-08-01), Imada et al.
patent: 3763008 (1973-10-01), Nakayama et al.
patent: 4381344 (1983-04-01), Rideout et al.
Tarr, H. L. A., Methods in Enzymology, vol. XII, Part A, pp. 113-118, 1968.
The Condensed Chemical Dictionary, 5th Ed., Reinhold Publishing Corp., pp. 348-349, 792-793, 1956.

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