Process for producing 3-chloromethyl-3-alkyloxetanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D30500

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active

058861998

ABSTRACT:
The present invention is to provide for a process for producing 3-chloromethyl-3-alkyloxetanes from a 1,1-bis(chloromethyl)-1-hydroxymethylalkane or its carboxylate ester through a dehydrogen chloride reaction or a deacid chloride reaction in an aqueous solution or suspension of an alkaline compound. The reaction is conducted, either in the presence of a phase transfer catalyst or an anion exchange resin having an ammonium group, or, while distilling the formed 3-chloromethyl-3-alkyloxetane out azeotropically with water. The invention enables one to produce 3-chloromethyl-3-alkyloxetanes within a shorter period of time and with a higher yield, and thus the process is much advantageous and useful from the industrial points of view.

REFERENCES:
patent: 5703194 (1998-02-01), Malik et al.
Tsukamoto, A et al., "Poly(vinyl chloride) compositions " CA80: 84266, 1984.
Miura et al., "3-Chloromethyl-3-Ethyloxacyclobutane," Chemical Abstracts, vol. 61, 11971-11972 (1964).
Petrova et al., "Synthesis of Oxacyclobutane Derivatives from the Trihydric Alcohols, Methyltrimethyolomethane," Chemical Abstracts, vol. 64, 14153-14154 (1966).

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