Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Reexamination Certificate
2006-06-06
2006-06-06
Keys, Rosalynd (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
C562S433000, C562S441000, C562S443000, C562S452000, C562S457000, C562S553000, C562S567000, C560S160000
Reexamination Certificate
active
07057066
ABSTRACT:
The present invention provides a process for preparing 3-amino-2-hydroxypropionic acid derivatives (1) which does not use dangerous reagents, is economically advantageous, and is suitable for an industrial production, which process comprises:treating N-protected-3-amino-2-hydroxypropionic acid derivatives (2) having a steric configuration at 2-position carbon reverse to that of derivatives (1) with a leaving group-introducing agent to convert into N-protected-3-aminopropionic acid derivatives (3),then treating the derivatives with a basic substance to convert into substituted-3-amino-2-hydroxypropionic acid derivatives (4) having an inverted steric configuration at 2-position carbon,and then converting the derivatives into 3-amino-2-hydroxypropionic acid derivatives (1).
REFERENCES:
patent: 4294966 (1981-10-01), Zergenyi
patent: 4296242 (1981-10-01), Nagabhushan et al.
patent: 156279 (1985-10-01), None
patent: 435068 (1991-07-01), None
patent: 0 885 879 (1998-12-01), None
patent: 930292 (1999-07-01), None
patent: 32-1323 (1957-02-01), None
patent: 32-002675 (1957-05-01), None
patent: 32-2675 (1957-05-01), None
patent: 36-21317 (1961-11-01), None
patent: 37-4310 (1962-06-01), None
patent: 58-35152 (1983-03-01), None
patent: 64-22849 (1989-01-01), None
patent: 6-179641 (1994-06-01), None
patent: WO 96/07642 (1996-03-01), None
Beresford, Kenneth J. M. et al., “Versatile Synthesis of L-α-Amino Acids Stereospecifically Labelled on the β-Carbon Atom”, TETRAHEDRON, vol. 52, No. 29, Jul. 1996, pp. 9891-9900.
Gou, Da-Ming et al., “A Practical Chemoenzymatic Synthesis of the Taxol C-13 Side Chain N-Benzoyl-(2R,3S)-3-phenylisoserine”, J. Org. Chem., vol. 58, No. 5, 1993, pp. 1287-1289.
Lee, Sang-Hyeup et al., “Efficient asymmetric synthesis of 2,3-diamino-3-phenylpropanoic acid derivatives”, TETRAHEDRON, vol. 57, No. 11, Mar. 2001, pp. 2139-2145.
Lee, Sang-Hyeup et al., “Efficient Syntheses and Ring-Opening Reactions of trans- and cis-Oxazoline-5-carboxylates”, Organic Letters, vol. 2, No. 9, May 2000, pp. 1243-1246.
Murao Hiroshi
Takeda Toshihiro
Ueda Yasuyoshi
Yamashita Koki
Foley & Lardner LLP
Kaneka Corporation
Keys Rosalynd
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