Process for producing 3-(3,4-dihydroxyphenyl) serine

Details Process for producing 3-(3,4-dihydroxyphenyl) serine Process for producing 3-(3,4-dihydroxyphenyl) serine

1984-05-25

1985-12-31

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562444, C07D20948, C07C 9912

Patent

active

045622639

ABSTRACT:
A process for producing racemic or optically active threo- or erythro-3-(3,4-dihydroxyphenyl)serine which comprises phthaloylating the amine group of a racemic or optically active threo- or erythro-3-(3,4-dihydroxyphenyl)serine derivative to yield a racemic or optically active threo- or erythro-N-phthaloyl-3-(3,4-dihydroxyphenyl)serine derivative and removing the phthaloyl group from the racemic or optically active threo- or erythro-N-phthaloyl-3-(3,4-dihydroxyphenyl)-serine to yield the racemic or optically active threo- or erythro-3-(3,4-dihydroxyphenyl)serine.

REFERENCES:
patent: 3723514 (1973-03-01), Hegedus et al.
patent: 4242256 (1980-12-01), Sharpe et al.
patent: 4275217 (1981-06-01), Duhamal et al.
patent: 4319040 (1982-03-01), Ohashi et al.
Hoffmann et al., J. Org. Chem., vol. 27, pp. 4686-4688 (1962).
Fieser et al., "Reagents For Organic Synthesis", pp. 111-112, 882 (1967).

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