Process for producing 10.dbd.dihydrosteffimycin and 10.dbd.dihyd

Details Process for producing 10.dbd.dihydrosteffimycin and 10.dbd.dihyd Process for producing 10.dbd.dihydrosteffimycin and 10.dbd.dihyd

1980-03-12

1981-04-28

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435254, 435827, 435911, C12P 1946, C12N 114

Patent

active

042647266

ABSTRACT:
Antibiotics 10-dihydrosteffimycin (U-58,875), and 10-dihydrosteffimycin B (U-58,874) are produced by carbon 10 ketonic carbonyl reduction in fermentation processes using the known antibiotics steffimycin and steffimycin B, respectively, as starting materials. These novel antibiotics are active against various microorganisms, for example, Bacillus subtilis, Bacillus cereus, Sarcina lutea, Streptococcus pyogenes, and Mycobacterium avium. Thus, these antibiotics can be used to inhibit the growth of the above microorganisms in various environments.

REFERENCES:
patent: 3309273 (1967-03-01), Bergy et al.
patent: 3794721 (1974-02-01), Brodasky et al.

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