Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1982-04-30
1985-08-13
Love, Ethel G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544359, 546197, 548526, 549443, C07D41300, C07D40300, C07D31744
Patent
active
045351597
ABSTRACT:
The present invention relates to a process for producing novel 1-position amino-derivatives of 1-(3',4'-methylenedioxyphenyl)propane-2-ol having general formula I: ##STR1## where R.sub.1 and R.sub.2 are hydrogen, alkyl having 1 to 2 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, or benzyl, with the proviso that R.sub.1 and R.sub.2 are not at the same time hydrogen, cycloalkyl or benzyl and where, R.sub.1 and R.sub.2 taken together with the nitrogen atom to which they are attached form a ring having 5 to 7 bonds, which may contain another heteroatom selected from oxygen or nitrogen which can be substituted by benzyl or hydroxyl, as well as the non-toxic addition salts of such derivatives.
REFERENCES:
patent: 2088941 (1937-08-01), Bockmuhl et al.
patent: 2578696 (1951-12-01), Gump et al.
patent: 2765307 (1956-10-01), Schmidle
patent: 3657244 (1972-04-01), Mentrup et al.
patent: 3915969 (1975-10-01), Manghisi et al.
Chemical Abstracts, 98: 53375f, (1983).
Foguet Rafael
Forne Ernesto
Ortiz José A.
Sacristan Aurelio
Ferrer Internacional S.A.
Love Ethel G.
Striker Michael J.
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