Process for producing 1-.beta.-D-arabinofuranosylcytosine-5'-ste

Details Process for producing 1-.beta.-D-arabinofuranosylcytosine-5'-ste Process for producing 1-.beta.-D-arabinofuranosylcytosine-5'-ste

1987-03-23

1989-03-14

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 11, C07H 1910, C07H 100, A61K 3170

Patent

active

048125601

ABSTRACT:
Disclosed herein are a novel process for producing 1-.beta.-D-arabinofuranosylcytosine-5'-stearylphosphate monosodium salt, which has been expected as an oral antitumor agent, and 1-.beta.-D-arabinofranosylcytosine-5'-stearylphosphate monosodium salt monohydrate obtained from the above-mentioned monosodium salt.

REFERENCES:
patent: 4542021 (1985-09-01), Kodama et al.
Saneyoshi et al, Chem. Phar. Bull., 28(10), 2915-2923.
Proceedings of The Japanese Cancer Association, the 35th Annual Meeting, 476: 133 (Oct. 1976).

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