Process for preparing xerosin II and xerosin III, improved biolo

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Processes of making – purifying or recovering

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424115, 435170, 435824, A61K 3574

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active

048776165

ABSTRACT:
A water-soluble complex which is isolable from acid-precipitable material recovered from cultures of the bacterium, Achromobacter xerosis, and which is effective in inducing a variety of therapeutic responses commonly associated with biological responses modifiers and anti-inflammatory agents and which exhibits significant therapeutic activity in higher vertebrates at a dosage ranging from about 0.1 to about 25.0 mg/kg of body weight. Also disclosed are compositions containing such complexes, methods of preparation with such complexes and methods of treatment with compositions having such complexes.

REFERENCES:
patent: 3039923 (1962-06-01), Groupe et al.
"Effect of Chemotherapy on the dissemination of cancer and metastases", Franchi, G.; Donelli, M. and Rosso, R. CA 73(15): 75492c.
"Effect of some drugs on tumor dissemination and metastases", Rosso, R.; Donelli, M.; Franchi, G. and Garattini, S. CA 73(9): 43627j.

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