Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2007-06-12
2007-06-12
Lukton, David (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C514S130000, C514S458000, C558S087000, C558S089000, C558S177000
Reexamination Certificate
active
10498013
ABSTRACT:
A process for making water-soluble phosphonooxymethyl ethers of hindered alcohol and phenol containing pharmaceuticals, such as camptothecin, propofol, etoposide, Vitamin E and Cyclosporin A. In particular, the process for preparing water-soluble phosphonooxymethyl derivatives comprises the steps of Formula (i) and Formula (ii); R—OH represents an alcohol- or phenol-containing drug, n represents an integer of 1 or 2, R1is hydrogen, an alkali metal ion, or a pharmaceutically acceptable cation, and R2is hydrogen, an alkali metal ion, or a pharmaceutically acceptable cation
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Bonneville George
Delahanty Greg
Walz Andrew J.
Banner & Witcoff , Ltd.
Lukton David
MGI GP, Inc.
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