Process for preparing virus-inactivated immunoglobulin solutions

Details Process for preparing virus-inactivated immunoglobulin solutions Process for preparing virus-inactivated immunoglobulin solutions

1994-10-26

1997-07-15

Eisenschenk, Frank C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

530415, 530416, 5303891, 5303901, C07K 1600, C07K 114, C07K 120

Patent

active

056484720

ABSTRACT:
This invention describes a process for preparing virus-inactivated immunoglobulin solutions suitable for intra-venous application, characterized in that the immunoglobulin is treated with non-ionic surfactants which subsequently are removed by solid-phase extraction on hydrophobic materials.

REFERENCES:
patent: 4789545 (1988-12-01), Woods et al.
patent: 5094960 (1992-03-01), Bonomo
Prince et al., PNAS, USA, 85:6944, 1988, Failure. HIV.

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