Process for preparing virus-inactivated factors 1X and X by...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S238000, C210S656000

Reexamination Certificate

active

06893856

ABSTRACT:
Disclosed is a process for preparing agents containing virus-inactivated vitamin K-dependent plasma components as well as protein C, protein S, factors II, VII, IX and/or X as well as combinations thereof, such as, for example, PPSB preparations, wherein a source containing these components is subjected to a appropriate separation procedures, especially by using membrane-chromatographic methods.

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Journal of Chromatography, vol. 632, Feb. 19, 1993, Amsterdam NL, pp. 1-10, Josic D. et al.
Journal of Chromatography, vol. 590, 1992, Amsterdam NL, pp. 59-76, Josic D. et al.

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