Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles
Reexamination Certificate
2006-07-24
2010-06-22
Chung, Susannah (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitriles
Reexamination Certificate
active
07741507
ABSTRACT:
The invention relates to novel compound of formula (IV), which is an organic acid salt of N-[(2′-cyanobiphenyl-4-yl)methyl]-(L)-valine ester. This compound is an useful intermediate for process of preparation of Valsartan of formula (I), chemically known as (S)—N-(1-Carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2′-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]amine. This invention also relates to a process for preparing Valsartan using novel intermediate of formula (IV).
REFERENCES:
patent: 5399578 (1995-03-01), Buhlmayer et al.
patent: 6589547 (2003-07-01), Igari et al.
patent: 2003/0068374 (2003-04-01), Kamei et al.
Ghotikar Ravindra Charudatta
Pandey Anand Kumar
Shah Hetal Remeshchandra
Soni Rohit Ravikant
Vasoya Sanjay Lakhabhai
Alembic Limited
Chung Susannah
Hamre Schumann Mueller & Larson P.C.
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