Process for preparing tunicamycin

Details Process for preparing tunicamycin Process for preparing tunicamycin

1981-03-13

1982-06-22

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435253, 435893, C12P 1960, C12N 120, C12R 152

Patent

active

043363334

ABSTRACT:
Tunicamycin is produced by the cultivation of Streptomyces chartreusis Calhoun and Johnson, 1956, NRRL 12338. Methods of recovering tunicamycin and for separating and isolating individual factors A.sub.1, A.sub.2, B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1 and D.sub.2 from tunicamycin complex are described.

REFERENCES:
patent: 3960667 (1976-06-01), Gale et al.
patent: 4237225 (1980-12-01), Hamill
A. Takatsuki et al., J. Antibiot. 24, 215-238 (1971).
K. Ekhardt et al., J. Antibiot. 28, 274-279 (1975).
A. Takatsuki et al., Agric. Biol. Chem. 41, 2307-2309 (1977).
A. Takatsuki et al., Agric. Biol. Chem. 43, 761 (1979).

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