Process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-n

Details Process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-n Process for preparing threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-n

1982-02-08

1983-12-13

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

2604297, C07C14940

Patent

active

044206283

ABSTRACT:
A threo-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)propionic ester of the formula: ##STR1## wherein R is an ester residue, is prepared by condensing a trans-3-(4-methoxyphenyl)glycidic ester of the formula: ##STR2## wherein R is the same as defined above, with 2-nitrothiophenol in the presence of a Lewis acid.

REFERENCES:
Kugita, Chem. Pharm. Bull., 18, pp. 2028-2037, 2284-2289, (1970).

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