Process for preparing thiazole derivative and the...

Details Process for preparing thiazole derivative and the... Process for preparing thiazole derivative and the...

2007-07-10

2007-07-10

McKane, Joseph K. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10513408

ABSTRACT:
The present invention provides a process for preparing thiazole derivatives of formula (XI), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPARδ), and also provides processes for compounds of formula (VI), (VII), (VIII) and (IX), intermediate compounds for preparation of the above compounds of formula (XI).

REFERENCES:
patent: 2005/0159598 (2005-07-01), Ingold et al.
patent: WO 99/46232 (1999-09-01), None
patent: WO 01/00603 (2001-01-01), None
patent: WO 02/50047 (2002-06-01), None
patent: WO 02/070011 (2002-09-01), None
Willson et al., STN International, HCAPLUS Database, Columbus, OH, Accession No. 2002:695816 (2006).
Marcos et al. “Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPAR delta)-synthesis and biological activity” Bioorg. Med. Chem. Lett. 13:1517-1521 (2003).
International Search Report for PCT/KR2003/000877, dated Jul. 15, 2003.
International Preliminary Examination Report for PCT/KR2003/000877, dated Aug. 18, 2004.

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