Process for preparing the combination products of triamterene an

Details Process for preparing the combination products of triamterene an Process for preparing the combination products of triamterene an

1987-12-16

1989-02-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424490, 424489, 424464, 424470, 424469, A61K 952

Patent

active

048045403

ABSTRACT:
A combination pharmaceutical composition is described, together with the process for manufacturing said pharmaceutical composition wherein the active ingredients, namely triamterene and hydrochlorothiazide, are incorporated into a solid dosage form via a single wet granulation process utilizing an acid component. Said process simplifies the formulation and manufacturing, permits greater uniformity, and increases in vitro dissolution.

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