Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-04-03
1990-05-08
Hollrah, Glennon H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549511, C07D30514
Patent
active
049240110
ABSTRACT:
Process for preparing taxol by the condensation of a (2R, 3S) acid of general formula (I) with a taxan derivative of general formula (II), followed by the removal of the groups R.sub.2 and R.sub.3 protecting the hydroxy groups. ##STR1##
REFERENCES:
patent: 4814470 (1989-03-01), Colin et al.
patent: 4857653 (1989-08-01), Colin et al.
Gue ritte-Voegelein et al, J. Natural Products, 50 (1), pp. 9-18, 1987.
Lataste et al, Pro. Natl. Acad. Sci. USA, 81, pp. 4090-4094, Jul. 1984.
Denis Jean-Noel
Greene Andrew E.
Guenard Daniel
Gueritte-Voegelein Francoise
Centre National de la Recherche Scientifique
Hollrah Glennon H.
Trinh Ba K.
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