Process for preparing synthetic matrix metalloprotease inhibitor

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564134, 564138, 564144, 562401, 562402, 562433, 562512, 562553, 562554, 562561, 562565, 562621, 562623, 548497, 548498, C07B 5700, C07C22718, C07C23516, C07D20920

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058921125

ABSTRACT:
Synthetic mammalian matrix metalloprotease inhibitors are disclosed that are useful for treating or preventing diseases wherein said diseases are caused by unwanted mammalian matrix metalloprotease activity and include skin disorders, keratoconus, restenosis, rheumatoid arthritis, wounds, cancer, angiogenesis and shock.

REFERENCES:
patent: 4558034 (1985-12-01), Galardy et al.
patent: 4599361 (1986-07-01), Dickens et al.
patent: 4743587 (1988-05-01), Dickens et al.
patent: 4996358 (1991-02-01), Handa et al.
patent: 5114953 (1992-05-01), Galardy et al.
patent: 5183900 (1993-02-01), Galardy et al.
patent: 5189178 (1993-02-01), Galardy et al.
patent: 5239078 (1993-08-01), Galardy et al.
patent: 5240958 (1993-08-01), Campion et al.
patent: 5268384 (1993-12-01), Galardy
patent: 5270326 (1993-12-01), Galardy et al.
Ogita et al. (1992) J. Antibiot, 45(11), 1723-1732.
Tanzawa et al, (1992) J. Antibiot., 45(11), 1733-1737.
Lundt, et al., Int.J. Peptide Protein Res. (1978) 12:258-268.
Masui et al., Bull. Chem. Soc. Jpn. 53:464-468 (1980).
Kortylewicz et al., J. Med. Chem. (1990) 33:(1):263-273.
Dean, J.Chem. Soc. (1965) 6655-6659.
Mata, et al., Tetrahedron Letters, 29:(52):6893-6896 (1988).
Bodanszky, et al., J. Peptide Protein Res. (1984) 23:565-572.
McMurry et al., Synthetic Communications 2(6), 389-394 (1972).
Landini et al., J. Org. Chem. (1982) 47:154-155.
Tozuka et al., J. of Antibiotics (Mar. 1983) 36(3):276-282.
Wang et al., Am. J. Physiol. (1990) 259:R645-R650.
Chaudry et al., Am. Jour. Surg. (1993) 165:2A(Suppl) 595-675.
Lindner et al, J. Clin.Invest. (1992) 90:2044-2049.
Wang et al. J.Surg.Res. (1991) 50:163-169.
Wang et al. J.Surg.Res. (1990) 48:464-470.
Gijbels, et al., Journal of Neuroimmunology (1992) 41:29-34.
Teba, et al., Circulatory Shock (1992) 91:121-129.
Galardy, Drugs of the Future (1993) 18(12):1109-1111.
Bird et al. (1994) J.Med.Chem. 37:158-169.
Chapman et al. (1993) J.Med.Chem. 36:4293-4301.
Beszant et al. (1993) J.Med.Chem. 36:4030-4039.
Naito et al. (1993) Agents Actions 39:182-186.
G. S. Schultz et al., "Treatment of Alkali-Injured Corneas With a Synthetic Inhibitor of Matrix Metalloprotease" Investigation Ophthalmology & Visual Science, vol. 33, No. 12, pp. 3325-3331, Nov. 1992.

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