Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1993-04-26
1995-09-19
Hollinden, Gary E.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
534588, 534856, 534869, 564395, 564409, 564414, 564420, 564421, 564422, 564423, 564434, 564435, C07C20922
Patent
active
054517028
ABSTRACT:
A process for preparing substituted aromatic amines is provided which comprises contacting a nucleophilic compound and an azo containing compound in the presence of a suitable solvent system, reacting the nucleophilic compound and the azo containing compound in the presence of a suitable base and a controlled amount of protic material at a temperature of about 10.degree. C. to about 150.degree. C. in a confined reaction zone wherein the molar ratio of protic material to base is 0:1 to about 5:1 and reducing the product of the reaction of the nucleophilic compound and the azo containing compound under conditions which produce the substituted aromatic amine. In another embodiment, the substituted aromatic amines of the invention are reductively alkylated to produce alkylated diamines or substituted derivatives thereof. In another embodiment, a process for preparing alkylated aromatic amines or substituted derivatives thereof is provided which comprises contacting a nucleophilic compound and an azo containing compound in the presence of a suitable solvent system, reacting the nucleophilic compound and the azo containing compound in the presence of a suitable base and a controlled amount of protic material at a temperature of about 10.degree. C. to about 150.degree. C. in a confined reaction zone wherein the molar ratio of protic material to base is 0:1 to about 5:1, and reductively alkylating the product of the reaction of nucleophilic compound and the azo containing compound under conditions which produce the alkylated aromatic amine or substituted derivative thereof.
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Cheng Brian K-M
Stern Michael K.
Bolding James C.
Burn B.
Goetz Kenneth D.
Hollinden Gary E.
Monsanto Company
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