Process for preparing spheroids of plant origin

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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424494, 424499, A61K 3578

Patent

active

057335516

ABSTRACT:
Compositions of natural, especially plant, constituents in the form of spheroids in particular of the medicinal type and formulations necessary to their preparation by a technical extrusion and spheronization system. Compositions characterized by the direct use of large quantities of solutions of natural, especially plant, origin such as liquid extracts adsorbed by natural or synthetic polymer-type substances. These various components are selected so that their combination permits the obtainment of a mass of a plasticity compatible with the technical extrusion and spheronization system. According to the process, liquid extract is prepared, this extract is incorporated in a substance of a polymeric type, the correctly moistened mass is extruded by micro-extrusion techniques and the extrudates are spheronized and then dried and calibrated.

REFERENCES:
Remington's Pharmaceutical Sciences, Mac Publishing Co., 18th Ed. "Spheronization", p. 164, 1990.

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