Process for preparing solid pharmaceutical dosage forms

Details Process for preparing solid pharmaceutical dosage forms Process for preparing solid pharmaceutical dosage forms

1995-05-09

1998-11-17

Harrison, Robert H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424485, 424488, A61K 900, A61K 920

Patent

active

058372873

ABSTRACT:
A process for the preparation of an oral solid rapidly disintegrating dosage form of a pharmaceutically active substance which has an unacceptable taste which process comprises forming a solution or a suspension in a solvent of a form of the pharmaceutically active substance which is less soluble in water and more palatable than the form with the unacceptable taste together with a water-soluble or water-dispersible carrier material, forming discrete units of the suspension or solution and removing the solvent from the discrete units under conditions whereby a network of the carrier material carrying a dosage of the less soluble and more palatable form of the pharmaceutically active substance is formed.

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