Process for preparing simvastatin having controlled ranges...

Details Process for preparing simvastatin having controlled ranges... Process for preparing simvastatin having controlled ranges...

2006-02-07

2006-02-07

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

06995277

ABSTRACT:
The present invention relates to a process for preparing simvastatin, wherein the simvastatin dimer content is controlled. More particularly, the present invention relates to a process for preparing simvastatin having a simvastatin dimer content of about 0.2 to about 0.4% wt. The present invention also relates to a process for preparing simvastatin having a simvastatin dimer content of less than about 0.2% wt. The present invention also discloses a commercial scale process of preparing simvastatin having a specified simvastatin dimer content which is reproducible.

REFERENCES:
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4582915 (1986-04-01), Sleteinger et al.
patent: 4820850 (1989-04-01), Verhoeven et al.
patent: 6797831 (2004-09-01), Dandala et al.
patent: 2002/0115712 (2002-08-01), Szabo et al.
patent: 0 351 918 (1990-01-01), None
patent: 511 867 (1992-11-01), None
patent: 0 864 560 (1998-09-01), None
patent: WO 98/32751 (1998-07-01), None
patent: WO 00/53566 (2000-09-01), None
patent: WO 01/34590 (2001-05-01), None
patent: WO 01/45484 (2001-06-01), None
patent: WO 02/20451 (2002-03-01), None
patent: WO 02/20457 (2002-03-01), None
patent: WO 03/018570 (2003-03-01), None

Affiliated with

Also associated with

Rating

Process for preparing simvastatin having controlled ranges... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing simvastatin having controlled ranges..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing simvastatin having controlled ranges... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3666130