Process for preparing side chain derivatives of cyclohexapeptidy

Details Process for preparing side chain derivatives of cyclohexapeptidy Process for preparing side chain derivatives of cyclohexapeptidy

1996-05-16

1997-07-08

Schain, Harold E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

930270, 930DIG546, 930DIG548, C07K 764, A61K 3812

Patent

active

056462450

ABSTRACT:
An improved process for the preparation of side chain derivatives of cyclohexapeptidyl lipopeptides represented by the formula ##STR1## wherein R.sup.1 is fully defined, is disclosed.

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patent: 5194377 (1993-03-01), Schwartz et al.
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patent: 5310873 (1994-05-01), Schmatz et al.
patent: 5378804 (1995-01-01), Balkovec et al.
patent: 5516756 (1996-05-01), Balkovec et al.
patent: 5552521 (1996-09-01), Belyk et al.
Schwartz, et al. J. Antibiotics, 45(12), pp. 1853-1866 (1992).
Bouffard, et al., J Med. Chem., 37(2) pp. 222-225 (1994).

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