Process for preparing (S)-.alpha.-methylarylacetic acids

Details Process for preparing (S)-.alpha.-methylarylacetic acids Process for preparing (S)-.alpha.-methylarylacetic acids

1992-05-04

1994-06-21

Marx, Irene

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435136, 435141, 435921, 4352554, C12P 740, C12P 754, C12N 114

Patent

active

053227913

ABSTRACT:
The invention relates to a process for preparing (S)-.alpha.-methylarylacetic acids from mixtures, such as racemic mixtures, of (R)- and (S)-.alpha.-methylarylacetic acid esters by enantiospecific hydrolysis using extracellular lipases of microbial origin (EC 3.1.1.3).

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B. Cambon et al., "Lipase-Catalyzed Production of Optically Active Acids . . . " Appl. Biochem. Biotech., 9, 255-60, 1984.
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