Process for preparing rifamycin S by hydrolysis of rifamycin O

Details Process for preparing rifamycin S by hydrolysis of rifamycin O Process for preparing rifamycin S by hydrolysis of rifamycin O

1974-10-24

1976-01-20

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D51520, C07D51510

Patent

active

039338010

ABSTRACT:
A process for preparing rifamycin S from rifamycin O. Rifamycin O is dissolved in a mixture of an organic solvent and an alcohol at room temperature. The rifamycin O is then hydrolyzed with a mineral acid and the thus obtained rifamycin S is purified by crystallization.

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