Process for preparing racemic 4-hydroxyphenylglycine

Details Process for preparing racemic 4-hydroxyphenylglycine Process for preparing racemic 4-hydroxyphenylglycine

1978-08-31

1980-05-27

Morgenstern, Norman

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07B 2000

Patent

active

042051851

ABSTRACT:
A process for the preparation of racemic 4-hydroxyphenylglycine, in which phenol, glyoxylic acid (or a salt thereof) and ammonia are reacted together to produce the desired 4-hydroxyphenylglycine.

REFERENCES:
patent: 2824128 (1958-02-01), Dexter
patent: 3000888 (1961-09-01), Biekert
Chemical Abstracts I, (Decombe), vol. 27, 2941, (1933).
Grillot et al., J. Amer. Chem. Soc., 67, 1968-1969 (1945).
Chemical Abstracts II, vol. 60, 1627e,f, (1964).
March, Advanced Organic Chemistry: Reactions, Mechanisms and Structures, McGraw-Hill, New York, (1968), pp. 424, 670-672.

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