Process for preparing R- and S-isomers of (R)-5-(2-(...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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H0002154

ABSTRACT:
A process for preparing optically pure enantiomers of R-(−)tamsulosin of formiula Ia and S-(+)tamsulosin of formula Ib by resolving racemic tamsulosin of formula I by means of (IR)-(−)-camphor-10-sulfonic acid and (1S)-(+)-camphor-10-sulfonic acid, resp., in an environment of organic solvents, water or mixtures thereof.

REFERENCES:
patent: 2003/0109752 (2003-06-01), Hoorn et al.

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