Process for preparing quinoline bases

Details Process for preparing quinoline bases Process for preparing quinoline bases

1996-07-11

1997-12-23

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546152, C07D21504

Patent

active

057009422

ABSTRACT:
There are provided processes for preparing quinolines by vapor phase reaction of a substituted or unsubstituted aniline base, formaldehyde and a C.sub.2 -C.sub.4 aldehyde wherein the aldehydes:aniline base molar ratio is at least 2:1. More preferred processes of the invention achieve high selectivities and yields of 8-methylquinoline, and high conversions of the aniline base.

REFERENCES:
patent: 3020280 (1962-02-01), Cislak et al.
patent: 3020281 (1962-02-01), Cislak et al.
patent: 3020282 (1962-02-01), Cislak et al.
patent: 4439607 (1984-03-01), Drabb
patent: 4617395 (1986-10-01), Dockner et al.
patent: 4723011 (1988-02-01), Doehner, Jr.

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