Process for preparing quinoline aldehyde and ketone derivatives

Details Process for preparing quinoline aldehyde and ketone derivatives Process for preparing quinoline aldehyde and ketone derivatives

1990-02-23

1991-03-12

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21514

Patent

active

049994310

ABSTRACT:
This invention relates to novel quinolyloxazole-2-ones which are useful as protein kinase C inhibitors, effective in the treatment of hypertension and asthma. This invention also includes a novel procedure for producing an intermediate ketone compound involving the reaction of a bromo-quinoline compound with butyl lithium and further reacting the lithiated compound with N-methyl-N-methoxyalkanamide.

REFERENCES:
patent: 1145487 (1915-07-01), Kaufmann
patent: 2798071 (1957-07-01), Mathes et al.
patent: 4670450 (1987-06-01), Schnettler et al.
patent: 4698353 (1987-10-01), Schnettler et al.
patent: 4866085 (1989-09-01), Schnettler et al.

Affiliated with

Also associated with

Rating

Process for preparing quinoline aldehyde and ketone derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing quinoline aldehyde and ketone derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing quinoline aldehyde and ketone derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-449258