Process for preparing pyrrolidinylacetamide derivatives

Details Process for preparing pyrrolidinylacetamide derivatives Process for preparing pyrrolidinylacetamide derivatives

1994-12-15

1995-10-24

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20127

Patent

active

054611571

ABSTRACT:
A process for preparing a 2-(1-pyrrolidinyl)acetamide derivative useful as a cerebral function improving agent is disclosed, comprising reacting a halogenoacetamide derivative with substituted or unsubstituted 2-pyrrolidinone, the halogenoacetamide derivative being prepared by reacting an amine and a halogenoacetyl chloride. High yields of the intermediate compound as well as the final product are attained at low cost.

REFERENCES:
patent: 5059687 (1991-10-01), Schroder et al.
Daskalov, Kh.; Georgiev, A.; Konstantinova, K.; (Bulgaria), Tr. Nauchnoizsled Khim.-Farm Inst., (1985). 15. p. 21-32 (and Abstract translated).
Yakugaku Zasshi (Pharmacological Journal), vol. 99(2), pp. 146-254 (1979).

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