Process for preparing pyrazolecarboxylic acid compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548377, 548378, 546279, C07D40100, C07D23114, C07D 5116

Patent

active

050535170

ABSTRACT:
There is disclosed a process for preparing a pyrazolecarboxylic acid derivative represented by the formula (II): ##STR1## wherein Y and Z each represent a hydrogen atom, a halogen atom, a nitro group, a cyano group, COOR.sub.1, NR.sub.1 R.sub.2, CONR.sub.1 R.sub.2, SR.sub.1, SO.sub.2 NR.sub.1 R.sub.2, SO.sub.2 R.sub.3, R.sub.3 CO, OR.sub.4, CHX.sub.2 or CX.sub.3 ; A represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a substituted or unsubstituted phenyl group, a substituted or unsubstituted pyridyl group or OR.sub.5 ; where R.sub.1 and R.sub.2 each represent a hydrogen atom or an alkyl group having 1 to 10 carbon atoms; R.sub.3 represents an alkyl group having 1 to 10 carbon atoms; R.sub.4 represents a hydrogen atom, an alkyl group having 1 to 10 carbon atoms, a substituted or unsubstituted phenyl group, CHF.sub.2, CF.sub.3 or CF.sub.3 CH.sub.2 ; R.sub.5 represents an alkyl group having 1 to 10 carbon atoms; and X represents a halogen atom,
which comprises oxidizing a pyrazole compound represented by the formula (I): ##STR2## wherein Y, Z and A have the same meanings as defined above, with an oxygen-containing gas in the presence of a metal compound catalyst.

REFERENCES:
patent: 3692828 (1972-09-01), Onopchenko et al.
patent: 3760009 (1973-09-01), Suzuki
patent: 4623726 (1986-11-01), Daniels
patent: 4794195 (1988-12-01), Hayashi et al.

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