Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2011-05-24
2011-05-24
Jiang, Shaojia Anna (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S027100, C536S027300, C536S028100
Reexamination Certificate
active
07947824
ABSTRACT:
The present invention for the stereoselective preparation of 2-deoxy-β-D-adenine nucleosides wherein a blocked 2-deoxy-α-D-arabinofuranosyl halide is coupled with the salt of an adenine derivative.
REFERENCES:
patent: 4751221 (1988-06-01), Watanabe et al.
patent: 5106837 (1992-04-01), Carson et al.
patent: 5206351 (1993-04-01), Markovac et al.
patent: 5262531 (1993-11-01), Kawakami et al.
patent: 5310732 (1994-05-01), Carson et al.
patent: 5384310 (1995-01-01), Montgomery et al.
patent: 5459256 (1995-10-01), Marquez
patent: 5506214 (1996-04-01), Beutler
patent: 5541164 (1996-07-01), Carson et al.
patent: 5661136 (1997-08-01), Montgomery et al.
patent: 5744597 (1998-04-01), Chou et al.
patent: 5821357 (1998-10-01), Chou et al.
patent: 6680382 (2004-01-01), Bauta et al.
patent: 6949640 (2005-09-01), Montgomery et al.
patent: 7528247 (2009-05-01), Bauta et al.
patent: 0314011 (1989-03-01), None
patent: WO89/08658 (1989-09-01), None
patent: 0428109 (1991-09-01), None
patent: WO95/32718 (1995-12-01), None
patent: WO01/60383 (2001-08-01), None
The Merck Index, 1996, pp. 13, 1229 and 1035.
Howell et al., Antiviral Nucleosides. A Stereospecific, Total Synthesis of 2′-Fluoro-2′-deoxy B-D-arabinofuranosyl Nucleosides, J. Org. Chem. vol. 53, No. 1:85-88, 1988.
Obara et al., New Naplanocin Analogues. 7. Synthesis and Antiviral Activity of 2-Halo Derivatives of Naplanocin A1, J. Med. Chem., vol. 39, No. 19:3847-3852, 1996.
Carson et al., Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine, Proc. Natl. Acad. Sci, USA, vol. 89, pp. 2970-2974, 1992.
Chu et al., Nucleosides. CXXXV. Synthesis of some 9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purines and their biological activities, Chemical and Pharmaceutical Bulletin,37, 2:336-339, 1989.
Bauta William E.
Burke Brian D.
Cantrell, Jr. William R.
Lovett Dennis P.
Puente Jose
Genzyme Corporation
Jiang Shaojia Anna
Krishnan Ganapathy
Verni, Esq. Christopher J.
LandOfFree
Process for preparing purine nucleosides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for preparing purine nucleosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing purine nucleosides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2664694