Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide
Patent
1994-07-07
1995-12-12
Knode, Marian C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using a micro-organism to make a protein or polypeptide
45 71, C12P 2100, G01N 33531
Patent
active
054749000
ABSTRACT:
A process for preparing a purified syphilis antigen from Treponema pallidum is presented. The process comprises the steps of obtaining an extract from Treponema pallidum, adsorbing the extract onto hydroxyapatite gel and eluting the antigen in the presence of a surfactant. The preferred surfactant is octylglucopyranoside, A diagnostic agent is prepared which comprises the purified syphilis antigen adsorbed on an inert carrier, which carrier at least partially a hydrophobic carrier to which the antigen is adsorbed.
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Ishikawa Fumio
Matsumoto Mie
Nagahara Kouhei
Knode Marian C.
Sekisui Chemical Co. Ltd.
Weber Jon P.
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