Process for preparing primycin salts

Details Process for preparing primycin salts Process for preparing primycin salts

1985-07-02

1988-11-01

Brown, J. R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536122, C07H 1504

Patent

active

047821418

ABSTRACT:
This invention relates to salts of primycin formed with an organic acid--preferably a C.sub.1-16 aliphatic carboxylic acid, a halogenated carboxylic acid, an aliphatic dicarboxylic acid, an aromatic carboxylic acid, a substituted aromatic carboxylic acid or an organic sulfonic acid--or an inorganic acid--preferably a hydrohalogenic acid.
There is furtheron provided a process for the preparation of new primycin salts which comprises reacting a suspension of primycin sulfate formed with an aliphatic alcohol containing 1-4 carbon atoms with a barium salt.
The new primycin salts of the present invention possess excellent antibiotic properties.

REFERENCES:
patent: 2518135 (1950-08-01), Gaver
patent: 2609368 (1952-09-01), Gaver
patent: 3244590 (1966-04-01), Schaffner et al.
patent: 3498884 (1970-03-01), Valyi-Nagy et al.
patent: 4035568 (1977-07-01), Schaffner et al.
patent: 4404189 (1983-09-01), Kulsar et al.
Merck Index, 10th Edition, Compound 7652.

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