Process for preparing pravastatin sodium

Details Process for preparing pravastatin sodium Process for preparing pravastatin sodium

2007-05-29

2007-05-29

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

Reexamination Certificate

active

10490937

ABSTRACT:
The present invention relates to a process for preparing pravastatin sodium. More specifically, in the process for preparing pravastatin sodium by adding a precursor of the pravastatin to a microorganism-culturing medium to obtain pravastatin sodium, the precursor of the pravastatin is added to a culture medium that is culturingStreptomyces carbophilusKBT229 (KCCM-10317), which is obtained by UV-mutating aStreptomyces carbophilusFERM BP-1145, and cultured to obtain the pravastatin sodium with high density and high efficiency.

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