Process for preparing polyamine derivatives and intermediates th

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

564511, C07C21109

Patent

active

058746277

ABSTRACT:
A process for preparing polyamines of the formula ##STR1## by selective introduction of the groups Z--CH.sub.2 -- at the terminal nitrogens from a polyamine having no nitrogen substituents by formation of bis-hexahydropyrimidine derivative, acylation, reduction of acyl group to give Z--CH.sub.2 --, and solvolysis.

REFERENCES:
patent: 5109024 (1992-04-01), Prakash et al.
Nagarajan, et al., J. Org. Chem. 51:4856-4861 (1986).
Weiberth, et al., J. Org. Chem. 51:5338-5341 (1986).
Edwards, et al., Tetrahedron Letters 31(24):3417-3420 (1990).
Edwards, et al., et al., J. of Med. Chem. 33:1369-1375 (1990).
Edwards, et al., J. of Med. Chem. 34:2414-2420 (1991).
Ganem, Acc. Chem. Res. 15:290-298 (1982).
Bowlin, et al., Cancer Research 51:62-66 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Process for preparing polyamine derivatives and intermediates th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing polyamine derivatives and intermediates th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing polyamine derivatives and intermediates th will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-308876

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.