Process for preparing piperazinyl quinolone derivatives

Details Process for preparing piperazinyl quinolone derivatives Process for preparing piperazinyl quinolone derivatives

1990-08-02

1991-09-24

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544363, C07D41314, C07D40104

Patent

active

050515055

ABSTRACT:
A novel process for preparing piperazinyl quinolone derivatives of the formula (I) is disclosed. The process comprises reacting dihaloquinolones with piperazine derivatives and tetraalkyl ammonium halides in the presence of a polar solvent such as acetonitrile, dimethylformamide, pyridine, sulfolane and dimethyl sulfoxide. ##STR1##

REFERENCES:
patent: 4460587 (1984-07-01), Vlattas
Vattas, "Chemical Abstracts", vol. 101, 1984, Col. 101:211186g.

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