Process for preparing perfluorochemical emulsion artificial bloo

Details Process for preparing perfluorochemical emulsion artificial bloo Process for preparing perfluorochemical emulsion artificial bloo

1983-08-19

1985-02-05

Rosen, Sam

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514756, 514743, 514832, A61K 3113, A61K 3102

Patent

active

044978294

ABSTRACT:
Particles of perfluoro compound with a lipid coating are emulsified by sonification in aqueous medium, wherein the proportion of perfluoro compound in the emulsion is preferably about 30-75% (w/v) and the proportion of lipid is preferably about 7-9% (w/v). In the resulting stable emulsion 95% of these particles having diameters less than 0.2.mu.. The emulsion is useful as an artificial blood for transport and delivery of oxygen to body tissues.

REFERENCES:
patent: 3958014 (1976-05-01), Watanabe et al.
patent: 3962439 (1976-06-01), Yokoyama et al.
patent: 4105798 (1978-08-01), Moore et al.
patent: 4133874 (1979-01-01), Miller et al.
patent: 4252827 (1981-02-01), Yokoyama et al.
Green Cross Corporation, "Technical Information Ser. No. 1", Dated May 15, 1975, pp. 38-39.

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