Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process...
Reexamination Certificate
2003-08-11
2009-02-17
Swope, Sheridan (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Reexamination Certificate
active
07491507
ABSTRACT:
Use of a lactic acid bacterium comprising a cell wall proteinase of around 200 kDa to prepare peptides with anti-hypertensive properties and a method for obtaining such a lactic acid bacterium.
REFERENCES:
patent: 0058074 (1982-08-01), None
patent: 0 737 690 (1996-10-01), None
patent: 0821968 (1998-02-01), None
patent: 1016709 (2000-07-01), None
patent: 01/32836 (2001-05-01), None
patent: WO 01/32836 (2001-05-01), None
patent: WO 01/32905 (2001-05-01), None
Maeno et al., Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase fromLactobacillus helveticusCP790. J Dairy Sci. Aug. 1996;79(8):1316-21.
Yamamoto et al., Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented byLactobacillus helveticusCPN4. J Dairy Sci. Jul. 1999(b) ;82(7):1388-93.
GenEmbl database Accession No. CQ759881 Mar. 3, 2004 Pridmore et al. Alignment with SEQ ID No. 1.
Guo et al, Protein tolerance to random amino acid change. Proc Natl Acad Sci U S A. Jun. 22, 2004;101(25):9205-9210. Epub Jun. 14, 2004.
Jeffrey A. Pederson et al., “Genetic characterization of a cell envelope-associated proteinase fromLactobacillus helveticusCNRZ32,” Journal of Bacteriology, Aug. 1999, pp. 4592-4597, vol. 181, No. 15.
Naoyuki Yamamoto et al., “Molecular cloning and sequence analysis of a gene encoding an extracellular proteinase fromLactobacillus helveticusCP790,” Biosci. Biotechnol. Biochem. 64 (6), pp. 1217-1222, 2000.
Anders Fuglsang et al., “Cardiovascular effects of fermented milk containing angiotensin-converting enzyme inhibitors evaluated in permanently catheterized, Spontaneously hypertensive rats,” Applied and Environmental Microbiology, Jul. 2002, pp. 3566-3569.
Gobbetti et al., “Production of Angiontensin-I-Converting-Enzyme-Inhibitory Peptides in Fermented Milks Started byLactobacillus delbrueckiisubsp.bulgaricusSS1 andLactococcus lactissubsp.cremorisFT4,” Applied and Environmental Microbiology, Sep. 2000, p. 3898-3904, vol. 66, No. 9, American Society for Microbiology.
Lowry et al., “Protein Measurement with the Folin Phenol Reagent,” J. Biol. Chem, 1951, 193:265-275.
Yamamoto et al., “Antihypertensive Effect of the Peptides Derived from Casein by an Extracellular Proteinase fromLactobacillus helveticusCP790,” 1994, J. Dairy Sci., 77:917-922.
Shin et al., “His-His-Leu, an Angiotensin I Converting Enzyme Inhibitory Peptide Derived from Korean Soybean Paste, Exerts Antihypertensive Activity in Vivo,” J. Agric. Food Chem., 2001, 49, pp. 3004-3009, American Chemical Society.
Flambard, “Role of bacterial cell wall proteinase in antihypertension,” Sciences Des Aliments, 22(2002) pp. 209-222.
International Search Report dated Dec. 3, 2003 for PCT/DK03/00522.
Fitzgerald, et al., “Milk protein-derived peptide inhibitors of angiotensin-I-converting enzyme,” British Journal of Nutrition 84:S33-S37 (Suppl. I 2002).
Gobetti, et al., “Production to Angiotensin-I-Converting-Enzyme-Inhibitory Peptides in Fermented Milks Started byLactobacillus delbrueckiisubsp.bulgaricusSS1 andLactococcus lactissubsp.cremorisFT4” Applied and Environmental Microbiology, vol. 66, No. 9, p. 3898-3904 (Sep. 2000).
Nakamura, et al., “Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors toangiotensin-I-converting enzyme,” J. Dairy Sci. 78: 1253-1257 (1995).
Yamamoto, et al., “Antihypertensive effect of the peptides derived from casein by an extracellular proteinase fromLactobacillus helveticusCP790,” J. Dairy Sci. 77:917-922 (1994).
Meisel, et al., “Bioactive peptides encrypted in milk proteins: proteolytic activation and thropho-functional properties”, Antonie van Leeuwenhoek 76: 207-215 (1999).
Law, et al., Proteolytic enzymes of lactic acid bacteria, Int., Dairy Journal 7(1):1-11 (1997).
Yin, et al., “Effect of lactic acid bacterial fermentation on the characteristics of minced mackerel,” Journal of Food Science 67(2):786-792 (2002).
Flambard, “ Role of bacterial cell wall proteinase in antihypertension, ” Sciences Des Aliments 22:209-222 (2002).
Shin, et al., “His-His-Leu, an angiotensin I converting Enzyme inhibitory peptide derived from Korean soybean paste, exerts antihypertensive activty in vivo,” J.Agric. Food Chem. 49:3004-3009 (2001).
International Search Report dated Dec. 3, 2002 for International Application No. PCT/DK03/00522.
International Search Report dated Aug. 31, 2004 for International Application No. PCT/DK2004/000239.
Altschul, et al., “Basic Local Alignment Search Tool” J. Mol. Biol. 215:403-410 (1990).
McGinnis, et al., “Blast: at the core of a powerful and diverse set of sequence analysis tools,” Nucleic Acids Research 32:W20-W25 (Web Server issue 2004).
Maniatis, et al., “Molecular Cloning: A laboratory manual,” (Cold Spring Harbor Laboratories, 2nd ed., vol. 3 1989).
Ausbel, et al., Current protocols in molecular biology, (John Wiley and Sons 1995).
Teo, et al., Circulation 102:1748-1754 (2000).
Marmur, Journal of Molecular Biology 3:208-218 (1961).
Chr. Hansen A/S
Hunton & Williams
Swope Sheridan
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