Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-09-07
1990-03-27
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D49900, A61K 31425
Patent
active
049122134
ABSTRACT:
The present invention provides a process for preparing a penicillanic acid derivative of the formula ##STR1## which comprises reacting lead with a halogenated penicillanic acid derivative of the formula ##STR2## wherein X, Y, Z and R.sup.1 are as defined in the specification. The reaction is advantageously conducted in the presence of a metal having higher ionization tendency than lead such as aluminum, iron, magnesium or a mixture thereof.
REFERENCES:
patent: 4656263 (1987-04-01), Kellogg
patent: 4762920 (1988-08-01), Carroll
Kase Kenji
Kawahara Ichiro
Matsumura Kiyotoshi
Nakai Akira
Sasaoka Michio
Otsuka Kagaku Kabushiki Kaisha
Rizzo Nicholas S.
Taiho Pharmaceutical Company Limited
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