Process for preparing orotic acid and thioorotic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D23954, C07D23956

Patent

active

041139500

ABSTRACT:
A method for the preparation of orotic acid and thioorotic acid is described which includes the formation of carboxymethylene-hydantoin or -thiohydantoin and subsequent rearrangement and isolation of orotic acid and thioorotic acid, respectively.

REFERENCES:
patent: 2937175 (1960-05-01), Scriabine
Chemische Fabrik Benckiser, Chem. Abstr., vol. 54 (1960), 8867b.
Moriyama, Chem. Abstr., vol. 59 (1963), 3925.
Chkhivadze et al., Chem. Abstr., vol. 60 (1964), 10679f.

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