Process for preparing optically active trans-3-phenylglycidamide

Details Process for preparing optically active trans-3-phenylglycidamide Process for preparing optically active trans-3-phenylglycidamide

1997-03-06

1999-03-16

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549541, 549552, 549553, C07D30346, C07D30132

Patent

active

058832645

ABSTRACT:
Process for preparing optically active trans-3-phenylglycidamide compound, which comprises subjecting racemic trans-3-phenylglycidamide compound of the formula (I) ##STR1## wherein Ring A is substituted or unsubstituted benzene, and R.sup.1 is H or lower alkyl, to optical resolution using a microorganism having ability of preferentially hydrolyzing one of (2S,3R) isomer or (2R,3S) isomer thereof, and process for preparing an optically active 1,5-benzothiazepine derivative from the thus-obtained optically active trans-3-phenylglycidamide compound.

REFERENCES:
patent: 4341718 (1982-07-01), Kim et al.
patent: 4590188 (1986-05-01), Takeda et al.
patent: 4959359 (1990-09-01), Mohacsi et la.
patent: 5198557 (1993-03-01), Giordano et al.
patent: 5244803 (1993-09-01), Morei et al.
patent: 5283193 (1994-02-01), Yamamoto et al.
patent: 5571704 (1996-11-01), Ghirotto et al.

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