Process for preparing optically active nucleosides from chiral c

Details Process for preparing optically active nucleosides from chiral c Process for preparing optically active nucleosides from chiral c

1994-01-07

1996-12-03

Kunz, Gary L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 271, 536 281, C07H 100, C07H 1906, C07H 1916

Patent

active

055809731

ABSTRACT:
A process is disclosed for the preparation of optically active purine nucleosides, particularly nucleosides of formulae 1 and 2, nucleoside analogs and optically active intermediates of formula 3 which may be used in the preparation of nucleosides of the formula 4 as well as a purine nucleosides and nucleoside analogs. ##STR1## The process is directed to the preparation of such compounds, including novel such compounds in their respective .alpha.- and .beta.-anomeric forms, and the enantiomeric forms of these compounds. These compounds show various levels of anti-viral and/or anti-cancer activity.

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