Process for preparing optically active cyclohexanol derivatives

Details Process for preparing optically active cyclohexanol derivatives Process for preparing optically active cyclohexanol derivatives

1996-10-11

1998-05-26

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C 29145

Patent

active

057568634

ABSTRACT:
A process for producing an optically active cyclohexanol derivative represented by formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 1 to 4 carbon atoms, a hydroxyl group, or a protected hydroxyl group, comprising asymmetrically hydrogenating a cyclohexanone derivative in the presence of a catalyst system composed of a transition metal compound (e.g., transition metal complex), a base (e.g., KOH), and a nitrogen compound (e.g., an amine compound).

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patent: 5210332 (1993-05-01), Taketomi et al.
patent: 5227538 (1993-07-01), Buchwald et al.
patent: 5596113 (1997-01-01), Douglas et al.

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